Recovery Factors is very effective at supplying the nutrients needed to regulate the intestinal epithelial cells ( and supporting the digestive amino acid pools required for proper digestion and as such one can often see profound differences both in terms of the intestinal behavior and activity. These are likely to be short-term adjustments with a normalization in the long-term, but it does depend on the individual and their diet as to how regular the person is. There is a general move towards being more regular when taking Recovery Factors. After sometimes showing some initial brief worsening of gut symptoms, in our recent study people who improved showed an average 54.6% improvement in digestive symptoms. So if you have an initial gut symptoms, simply spread the dose throughout the day. In a few weeks, your gut will usually be functioning far better than before you began the supplement.